AIRP Rabbit Polyclonal Antibody

Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]) .[supplied by OMIM, Mar 2008], catalytic activity:A 5'-ribonucleotide + H (2) O = a ribonucleoside + phosphate., cofactor:Magnesium., enzyme regulation:Activated by ADP., function:Dephosphorylates the 5' and 2' (3') -phosphates of deoxyribonucleotides. Helps to regulate adenosine levels., function:Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected., similarity:Belongs to the 5'-nucleotidase type 3 family., similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family., tissue specificity:Expressed in brain, kidney, pancreas and placenta., tissue specificity:Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.