AIRP Rabbit Polyclonal Antibody
Product Specifications
Background
Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]) .[supplied by OMIM, Mar 2008], catalytic activity:A 5'-ribonucleotide + H (2) O = a ribonucleoside + phosphate., cofactor:Magnesium., enzyme regulation:Activated by ADP., function:Dephosphorylates the 5' and 2' (3') -phosphates of deoxyribonucleotides. Helps to regulate adenosine levels., function:Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected., similarity:Belongs to the 5'-nucleotidase type 3 family., similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family., tissue specificity:Expressed in brain, kidney, pancreas and placenta., tissue specificity:Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.
Product Name Alternative
NT5C1B; AIRP; FKSG85; Cytosolic 5'-nucleotidase 1B; cN1B; Autoimmune infertility-related protein; Cytosolic 5'-nucleotidase IB; cN-IB
Gene Name
NT5C1B
Gene ID
93034
Swiss Prot
Q96P26
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Purine metabolism; Pyrimidine metabolism; Nicotinate and nicotinamide metabolism
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
69kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
