Orexin R-1 Rabbit Polyclonal Antibody

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009], function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G (q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade., similarity:Belongs to the G-protein coupled receptor 1 family.