KIF2C Rabbit Polyclonal Antibody

Kinesin family member 2C (KIF2C) Homo sapiens This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], function:Present throughout the cell cycle, associates with centromeres at early prophase, and remains associated with the centromere until after telophase., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the kinesin-like protein family., similarity:Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily., similarity:Contains 1 kinesin-motor domain., subunit:Interacts with CENPH., tissue specificity:Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas.