InsP5 2-kinase Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6) . InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export. [provided by RefSeq, Nov 2010], catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + 1D-myo-inositol hexakisphosphate., domain:The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2., function:Phosphorylates Ins (1,3,4,5,6) P5 at position 2 to form Ins (1,2,3,4,5,6) P6 (InsP6 or phytate) . InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis., similarity:Belongs to the IPK1 type 2 family., tissue specificity:Ubiquitously expressed, with high expression in heart, brain, testis and placenta.
Product Name Alternative
IPPK; C9orf12; Inositol-pentakisphosphate 2-kinase; IPK1 homolog; Inositol-1; 3,4,5,6-pentakisphosphate 2-kinase; Ins (1,3,4,5,6) P5 2-kinase; InsP5 2-kinase
Gene Name
IPPK
Gene ID
64768
Swiss Prot
Q9H8X2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Inositol phosphate metabolism; Phosphatidylinositol signaling system
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
56kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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