Zhangfei Rabbit Polyclonal Antibody
Product Specifications
Background
Function:Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells., miscellaneous:Named Zhangfei after a legendary Chinese warrior who was contemporary with Luman in around 220 AD., similarity:Belongs to the bZIP family. ATF subfamily., similarity:Contains 1 bZIP domain., subcellular location:Colocalizes at punctate nuclear structures with CREB3 and HCFC1., subunit:Interacts with HCFC1, causing suppression of CREB3 transcriptional activity., tissue specificity:In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lungs. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver., function:Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells., miscellaneous:Named Zhangfei after a legendary Chinese warrior who was contemporary with Luman in around 220 AD., similarity:Belongs to the bZIP family. ATF subfamily., similarity:Contains 1 bZIP domain., subcellular location:Colocalizes at punctate nuclear structures with CREB3 and HCFC1., subunit:Interacts with HCFC1, causing suppression of CREB3 transcriptional activity., tissue specificity:In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lungs. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.
Product Name Alternative
CREBZF; ZF; CREB/ATF bZIP transcription factor; Host cell factor-binding transcription factor Zhangfei; HCF-binding transcription factor Zhangfei
Gene Name
CREBZF
Gene ID
58487
Swiss Prot
Q9NS37
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
26kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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