VAMP-4 Rabbit Polyclonal Antibody
Product Specifications
Background
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008], function:Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule., similarity:Belongs to the synaptobrevin family., similarity:Contains 1 v-SNARE coiled-coil homology domain., subcellular location:Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG) . Not found on the mature secretory organelles., subunit:Identified in a complex containing STX6, STX13, VAMP4 and VTI1A.
Product Name Alternative
VAMP4; Vesicle-associated membrane protein 4; VAMP-4
Gene Name
VAMP4
Gene ID
8674
Swiss Prot
O75379
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
ICC/IF, ELISA
Field of Research
SNARE interactions in vesicular transport
Purification
Affinity purification
Dilution
ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/APRab19706_Enkilife_EN.pdf
Isotype
IgG
Available Sizes
Curated Selection
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