ET-1 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015], function:Endothelins are endothelium-derived vasoconstrictor peptides., online information:Endothelin entry, similarity:Belongs to the endothelin/sarafotoxin family., tissue specificity:Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Product Name Alternative
EDN1; Endothelin-1; Preproendothelin-1; PPET1
Gene Name
EDN1
Gene ID
1906
Swiss Prot
P05305
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Melanogenesis
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
25kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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