NEDL2 Rabbit Polyclonal Antibody
Product Specifications
Background
Function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 C2 domain., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 2 WW domains., subunit:Interacts with TP73., tissue specificity:Predominantly expressed in adult brain, lung and heart., function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 C2 domain., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 2 WW domains., subunit:Interacts with TP73., tissue specificity:Predominantly expressed in adult brain, lung and heart.
Product Name Alternative
HECW2; KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2
Gene Name
HECW2
Gene ID
57520
Swiss Prot
Q9P2P5
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
140-150kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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