S-100P Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008], miscellaneous:This protein binds two calcium ions., similarity:Belongs to the S-100 family., similarity:Contains 2 EF-hand domains., subcellular location:Colocalizes with S100PBP in the nucleus., subunit:Homodimer. Interacts with S100PBP and S100Z., tissue specificity:Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
Product Name Alternative
S100P; S100E; Protein S100-P; Protein S100-E; S100 calcium-binding protein P
Gene Name
S100P
Gene ID
6286
Swiss Prot
P25815
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
10kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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