MRGX1 Rabbit Polyclonal Antibody

Function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) . BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha) q proteins are involved in the calcium-signaling pathway., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons., function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) . BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha) q proteins are involved in the calcium-signaling pathway., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.