DNAM-1 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015], function:Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell., PTM:Phosphorylated., similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with PVR and PVRL2., tissue specificity:Expressed by peripheral blood T-lymphocytes.
Product Name Alternative
CD226; DNAM1; CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226
Gene Name
CD226
Gene ID
10666
Swiss Prot
Q15762
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Cell adhesion molecules (CAMs)
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
38kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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