DNA pol α Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes the catalytic subunit of DNA polymerase, which together with a regulatory and two primase subunits, forms the DNA polymerase alpha complex. The catalytic subunit plays an essential role in the initiation of DNA replication. [provided by RefSeq, Mar 2010], catalytic activity:Deoxynucleoside triphosphate + DNA (n) = diphosphate + DNA (n+1) ., function:Polymerase alpha in a complex with DNA primase is a replicative polymerase., miscellaneous:In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis., PTM:A 165 kDa form is probably produced by proteolytic cleavage at Lys-124., similarity:Belongs to the DNA polymerase type-B family., subunit:Interacts with SV40 Large T antigen; this interaction allows viral DNA replication.
Product Name Alternative
POLA1; POLA; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180
Gene Name
POLA1
Gene ID
5422
Swiss Prot
P09884
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Purine metabolism; Pyrimidine metabolism; DNA replication
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
165kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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