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CD32-A Rabbit Polyclonal Antibody

Product Specifications

Background

Fc fragment of IgG receptor IIa (FCGR2A) Homo sapiens This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008], function:Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens., similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with INPP5D/SHIP1 and INPPL1/SHIP2, regulating its function., tissue specificity:Found on monocytes, neutrophils and eosinophil platelets.

Product Name Alternative

FCGR2A; CD32; FCG2; FCGR2A1; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD32

Gene Name

FCGR2A

Gene ID

2212

Swiss Prot

P12318

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, ELISA

Field of Research

Fc gamma R-mediated phagocytosis; Systemic lupus erythematosus

Purification

Affinity purification

Dilution

WB 1:500-1:2000, ELISA 1:10000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

34kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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