ABCC12 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008], developmental stage:Expressed in fetal tissues., function:Probable transporter., similarity:Belongs to the ABC transporter family. Conjugate transporter (TC 3.A.1.208) subfamily., similarity:Contains 2 ABC transmembrane type-1 domains., similarity:Contains 2 ABC transporter domains., tissue specificity:Expressed in testis (at protein level) . Widely expressed at low level. Isoform 5 is specifically expressed in brain, testis and breast cancer cells.
Product Name Alternative
ABCC12; MRP9; Multidrug resistance-associated protein 9; ATP-binding cassette sub-family C member 12
Gene Name
ABCC12
Gene ID
94160
Swiss Prot
Q96J65
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
ABC transporters
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
170kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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