FX Rabbit Polyclonal Antibody
Product Specifications
Background
Tissue specific transplantation antigen P35B is a NADP (H) -binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008], catalytic activity:GDP-L-fucose + NADP (+) = GDP-4-dehydro-6-deoxy-D-mannose + NADPH., function:Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction., pathway:Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-D-mannose: step 2/2., similarity:Belongs to the fucose synthetase family., subunit:Homodimer.
Product Name Alternative
TSTA3; SDR4E1; GDP-L-fucose synthase; GDP-4-keto-6-deoxy-D-mannose-3; 5-epimerase-4-reductase; Protein FX; Red cell NADP (H) -binding protein; Short-chain dehydrogenase/reductase family 4E member 1
Gene Name
TSTA3
Gene ID
7264
Swiss Prot
Q13630
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Fructose and mannose metabolism; Amino sugar and nucleotide sugar metabolism
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
40kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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