SPZ1 Rabbit Polyclonal Antibody

This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011], function:Transcription factor that binds to the DNA sequence 5'-CANNTG-3' (E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis., PTM:Phosphorylated by ERK1 and ERK2., similarity:Contains 1 basic helix-loop-helix (bHLH) domain., subunit:Interacts with PPP1CC isoform gamma-2., tissue specificity:Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.