CD300b Rabbit Polyclonal Antibody

CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]) .[supplied by OMIM, Mar 2008], function:Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitement of GRB2., PTM:Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2., similarity:Belongs to the CD300 family., similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., subunit:Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN., tissue specificity:Expressed exclusively in myeloid lineages.

CMRF35-like molecule 7 (CLM-7; CD300 antigen-like family member B; CMRF35-A2; Immune receptor expressed on myeloid cells 3; IREM-3; Leukocyte mono-Ig-like receptor 5; Triggering receptor expressed on myeloid cells 5; TREM-5; CD antigen CD300b)