Endo G-L1 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009], cofactor:Divalent metal cations., function:Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity., miscellaneous:The active site contains 1 hydrated divalent metal cation that has only 1 direct interaction with the protein; all other interactions are via water molecules., similarity:Belongs to the DNA/RNA non-specific endonuclease family., subunit:Homodimer., tissue specificity:Ubiquitous.
Product Name Alternative
EXOG; ENDOGL1; ENDOGL2; ENGL; Nuclease EXOG; mitochondrial; Endonuclease G-like 1; Endo G-like 1
Gene Name
EXOG
Gene ID
9941
Swiss Prot
Q9Y2C4
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Apoptosis_Inhibition; Apoptosis_Mitochondrial; Apoptosis_Overview
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
41kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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