NKp30 Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010], function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis., polymorphism:A genetic variation in NCR3 is associated with mild malaria suceptibility [MIM:609148]., similarity:Belongs to the natural cytotoxicity receptor (NCR) family., similarity:Contains 1 Ig-like (immunoglobulin-like) domain., subunit:Interacts with CD3Z., tissue specificity:Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.
Product Name Alternative
NCR3; 1C7; LY117; Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NKp30; CD antigen CD337
Gene Name
NCR3
Gene ID
259197
Swiss Prot
O14931
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Natural killer cell mediated cytotoxicity
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
30kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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