Malic enzyme 1 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008], catalytic activity: (S) -malate + NADP (+) = pyruvate + CO (2) + NADPH., cofactor:Divalent metal cations. Prefers magnesium or manganese., online information:The Singapore human mutation and polymorphism database, similarity:Belongs to the malic enzymes family., subunit:Homotetramer., tissue specificity:Expressed in all tissues tested including liver, placenta and white adipose tissue.
Product Name Alternative
ME1; NADP-dependent malic enzyme; NADP-ME; Malic enzyme 1
Gene Name
ME1
Gene ID
4199
Swiss Prot
P48163
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Pyruvate metabolism; PPAR
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
64kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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