Nesprin-3 Rabbit Polyclonal Antibody
Product Specifications
Background
Function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system., similarity:Belongs to the nesprin family., similarity:Contains 1 KASH domain., similarity:Contains 2 spectrin repeats., subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells., subunit:Interacts with actin-binding domain of PLEC1/plectin., function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system., similarity:Belongs to the nesprin family., similarity:Contains 1 KASH domain., similarity:Contains 2 spectrin repeats., subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells., subunit:Interacts with actin-binding domain of PLEC1/plectin.
Product Name Alternative
SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
Gene Name
SYNE3
Gene ID
161176
Swiss Prot
Q6ZMZ3
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ICC/IF 1:200-1:1000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
115kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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