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Nesprin-3 Rabbit Polyclonal Antibody

Product Specifications

Background

Function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system., similarity:Belongs to the nesprin family., similarity:Contains 1 KASH domain., similarity:Contains 2 spectrin repeats., subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells., subunit:Interacts with actin-binding domain of PLEC1/plectin., function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system., similarity:Belongs to the nesprin family., similarity:Contains 1 KASH domain., similarity:Contains 2 spectrin repeats., subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells., subunit:Interacts with actin-binding domain of PLEC1/plectin.

Product Name Alternative

SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3

Gene Name

SYNE3

Gene ID

161176

Swiss Prot

Q6ZMZ3

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, ELISA

Purification

Affinity purification

Dilution

WB 1:500-1:2000, ICC/IF 1:200-1:1000, ELISA 1:20000-1:40000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

115kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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