AMPD2 Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012], catalytic activity:AMP + H (2) O = IMP + NH (3) ., function:AMP deaminase plays a critical role in energy metabolism., pathway:Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1., similarity:Belongs to the adenosine and AMP deaminases family., subunit:Homotetramer., tissue specificity:Three isoforms are present in mammals: AMP deaminase 1 is the predominant form in skeletal muscle; AMP deaminase 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; AMP deaminase 3 is found in erythrocytes.
Product Name Alternative
AMPD2; AMP deaminase 2; AMP deaminase isoform L
Gene Name
AMPD2
Gene ID
271
Swiss Prot
Q01433
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Purine metabolism
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
100kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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