Nicalin Rabbit Polyclonal Antibody
Product Specifications
Background
Function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning., similarity:Belongs to the nicastrin family., subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex., tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart., function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning., similarity:Belongs to the nicastrin family., subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex., tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.
Product Name Alternative
NCLN; Nicalin; Nicastrin-like protein
Gene Name
NCLN
Gene ID
56926
Swiss Prot
Q969V3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
63kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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