GABAA Rβ2 Rabbit Polyclonal Antibody

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008], function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel., online information:Forbidden fruit - Issue 56 of March 2005, similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family., subunit:Generally pentameric. There are five types of GABA (A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1.