GRK 7 Rabbit Polyclonal Antibody

This gene encodes a member of the guanine nucleotide-binding protein (G protein) -coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008], catalytic activity:ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate., function:Phosphorylates cone opsins thereby initiating their deactivation., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 1 protein kinase domain., similarity:Contains 1 RGS domain., tissue specificity:Retina. Cones and rod.