PKAγ cat Rabbit Polyclonal Antibody

Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008], catalytic activity:ATP + a protein = ADP + a phosphoprotein., enzyme regulation:Activated by cAMP., function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 1 protein kinase domain., subunit:A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits., tissue specificity:Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.

MAPK_ERK_Growth; MAPK_G_Protein; Calcium; Chemokine; Oocyte meiosis; Apoptosis_Inhibition; Apoptosis_Mitochondrial; Apoptosis_Overview; Vascular smooth muscle contraction; WNT; WNT-T CELLHedgehog; Gap junction; Long-term potentiation; Olfactory transduction; Taste transduction; Insulin_Receptor; GnRH; Progesterone-mediated oocyte maturation; Melanogenesis; Prion diseases; Vibrio cholerae infection; Dilated cardiomyopathy