TGFβ RIII Rabbit Polyclonal Antibody
Product Specifications
Background
This locus encodes the transforming growth factor (TGF) -beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010], function:Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors., PTM:Extensively modified by glycosaminoglycan groups (GAG) ., similarity:Contains 1 ZP domain., subcellular location:Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix., subunit:Interacts with TCTEX1D4.
Product Name Alternative
TGFBR3; Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III
Gene Name
TGFBR3
Gene ID
7049
Swiss Prot
Q03167
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ICC/IF 1:50-1:200, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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