MEF-2B Rabbit Polyclonal Antibody

This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010], function:Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription., similarity:Belongs to the MEF2 family., similarity:Contains 1 MADS-box domain., similarity:Contains 1 Mef2-type DNA-binding domain., subunit:Interacts with HDAC7 (By similarity) . Heterodimer. Interacts with HDAC9., tissue specificity:Expressed in skeletal and cardiac muscle and brain.