HSF2 Rabbit Polyclonal Antibody

Heat shock transcription factor 2 (HSF2) Homo sapiens The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011], function:DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked., similarity:Belongs to the HSF family., subcellular location:Cytoplasmic during normal growth and moves to the nucleus upon activation., subunit:DNA-binding homotrimer in stressed or heat shocked cells, otherwise found as a homodimer.