HXK III Rabbit Polyclonal Antibody

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009], catalytic activity:ATP + D-hexose = ADP + D-hexose 6-phosphate., domain:The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus., enzyme regulation:Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P., miscellaneous:In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase) ., online information:Hexokinase entry, pathway:Carbohydrate metabolism; hexose metabolism., similarity:Belongs to the hexokinase family., subunit:Monomer.

Glycolysis / Gluconeogenesis; Fructose and mannose metabolism; Galactose metabolism; Starch and sucrose metabolism; Amino sugar and nucleotide sugar metabolism; Insulin_Receptor; Type II diabetes mellitus