APC1 Rabbit Polyclonal Antibody

This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011], function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis., similarity:Belongs to the APC1 family., similarity:Contains 4 PC repeats., subunit:The APC/C is composed of at least 11 subunits.