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APC1 Rabbit Polyclonal Antibody

Product Specifications

Background

This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011], function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis., similarity:Belongs to the APC1 family., similarity:Contains 4 PC repeats., subunit:The APC/C is composed of at least 11 subunits.

Product Name Alternative

ANAPC1; TSG24; Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein

Gene Name

ANAPC1

Gene ID

64682

Swiss Prot

Q9H1A4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC, ICC/IF, ELISA

Field of Research

Cell_Cycle_G1S; Cell_Cycle_G2M_DNA; Oocyte meiosis; Ubiquitin mediated proteolysis; Progesterone-mediated oocyte maturation

Purification

Affinity purification

Dilution

IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/antibody/APRab06996_Enkilife_EN.pdf

Isotype

IgG

Available Sizes

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