Fos B (phospho Ser27) Rabbit Polyclonal Antibody

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], function:FosB interacts with Jun proteins enhancing their DNA binding activity., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. Fos subfamily., similarity:Contains 1 bZIP domain., subunit:Heterodimer.