Fer (phospho Tyr402) Rabbit Polyclonal Antibody

The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Apr 2015], catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate., function:Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily., similarity:Contains 1 FCH domain., similarity:Contains 1 protein kinase domain., similarity:Contains 1 SH2 domain., subcellular location:Associated with the chromatin., tissue specificity:Expressed in a variety of lymphoid cell lines.

FER; TYK3; Tyrosine-protein kinase Fer; Feline encephalitis virus-related kinase FER; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; Proto-oncogene c-Fer; Tyrosine kinase 3; p94-Fer