MKP-7 Rabbit Polyclonal Antibody

Dual specificity phosphatase 16 (DUSP16) Homo sapiens This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010], catalytic activity:A phosphoprotein + H (2) O = a protein + phosphate., catalytic activity:Protein tyrosine phosphate + H (2) O = protein tyrosine + phosphate., function:Involved in the inactivation of MAP kinases., similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily., similarity:Contains 1 rhodanese domain., similarity:Contains 1 tyrosine-protein phosphatase domain.