ARHGAP1 Rabbit Polyclonal Antibody

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members. [provided by RefSeq, Aug 2012], function:GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate., similarity:Contains 1 CRAL-TRIO domain., similarity:Contains 1 Rho-GAP domain., subunit:Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with BNIPL., tissue specificity:Ubiquitous.

ARHGAP1; CDC42GAP; RHOGAP1; Rho GTPase-activating protein 1; CDC42 GTPase-activating protein; GTPase-activating protein rhoOGAP; Rho-related small GTPase protein activator; Rho-type GTPase-activating protein 1; p50-RhoGAP