AHA-1 Rabbit Polyclonal Antibody

Function:Cochaperone that stimulates HSP90 ATPase activity (By similarity) . May affect a step in the endoplasmic reticulum to Golgi trafficking., induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG) ., similarity:Belongs to the AHA1 family., subcellular location:May transiently interact with the endoplasmic reticulum., subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G) . Interacts with GCH1., tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta., function:Cochaperone that stimulates HSP90 ATPase activity (By similarity) . May affect a step in the endoplasmic reticulum to Golgi trafficking., induction:By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG) ., similarity:Belongs to the AHA1 family., subcellular location:May transiently interact with the endoplasmic reticulum., subunit:Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein (VSV G) . Interacts with GCH1., tissue specificity:Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.