NT5C1A Rabbit Polyclonal Antibody
Product Specifications
Background
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]) .[supplied by OMIM, Mar 2008], catalytic activity:A 5'-ribonucleotide + H (2) O = a ribonucleoside + phosphate., cofactor:Magnesium., enzyme regulation:Activated by ADP., function:Dephosphorylates the 5' and 2' (3') -phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia., similarity:Belongs to the 5'-nucleotidase type 3 family., tissue specificity:Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.
Product Name Alternative
NT5C1A; Cytosolic 5'-nucleotidase 1A; cN1A; Cytosolic 5'-nucleotidase IA; cN-I; cN-IA
Gene Name
NT5C1A
Gene ID
84618
Swiss Prot
Q9BXI3
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, ELISA
Field of Research
Purine metabolism; Pyrimidine metabolism; Nicotinate and nicotinamide metabolism
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ICC/IF 1:200-1:1000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
41kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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