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NT5C1A Rabbit Polyclonal Antibody

Product Specifications

Background

Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]) .[supplied by OMIM, Mar 2008], catalytic activity:A 5'-ribonucleotide + H (2) O = a ribonucleoside + phosphate., cofactor:Magnesium., enzyme regulation:Activated by ADP., function:Dephosphorylates the 5' and 2' (3') -phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia., similarity:Belongs to the 5'-nucleotidase type 3 family., tissue specificity:Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.

Product Name Alternative

NT5C1A; Cytosolic 5'-nucleotidase 1A; cN1A; Cytosolic 5'-nucleotidase IA; cN-I; cN-IA

Gene Name

NT5C1A

Gene ID

84618

Swiss Prot

Q9BXI3

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, ELISA

Field of Research

Purine metabolism; Pyrimidine metabolism; Nicotinate and nicotinamide metabolism

Purification

Affinity purification

Dilution

WB 1:500-1:2000, ICC/IF 1:200-1:1000, ELISA 1:10000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

41kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/antibody/APRab14919_Enkilife_EN.pdf

Isotype

IgG

Available Sizes

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