RIN3 Rabbit Polyclonal Antibody
Product Specifications
Background
Summary: This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016], caution:The region from Asp-168 to Pro-327 is deduced from the genomic sequence by similarity to the mouse sequence., function:Potential Ras effector protein. May function as a guanine nucleotide exchange (GEF), by exchanging bound GDP for free GTP., similarity:Belongs to the RIN (Ras interaction/interference) family., similarity:Contains 1 Ras-associating domain., similarity:Contains 1 SH2 domain., similarity:Contains 1 VPS9 domain., subcellular location:Activation of tyrosine phosphorylation signaling induces translocation to cytoplasmic vesicles., subunit:Interacts with RAB5B and BIN1., tissue specificity:Widely expressed.
Product Name Alternative
RIN3; Ras and Rab interactor 3; Ras interaction/interference protein 3
Gene Name
RIN3
Gene ID
79890
Swiss Prot
Q8TB24
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
107kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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