A Cyclase VII Rabbit Polyclonal Antibody

This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013], catalytic activity:ATP = 3',5'-cyclic AMP + diphosphate., cofactor:Binds 2 magnesium ions per subunit., function:This is a membrane-bound, calcium-inhibitable adenylyl cyclase., similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family., similarity:Contains 2 guanylate cyclase domains.

Purine metabolism; Calcium; Chemokine; Oocyte meiosis; Vascular smooth muscle contraction; Gap junction; GnRH; Progesterone-mediated oocyte maturation; Melanogenesis; Dilated cardiomyopathy