JIK Rabbit Polyclonal Antibody

Catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF) . When overexpressed, may activate ERK1/ERK2 and JNK/SAPK., PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., subcellular location:Also localized to the peripheral cell membrane., subunit:Self-associates., tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver., catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF) . When overexpressed, may activate ERK1/ERK2 and JNK/SAPK., PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., subcellular location:Also localized to the peripheral cell membrane., subunit:Self-associates., tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.

TAOK3; DPK; JIK; KDS; MAP3K18; Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhi