RMP Rabbit Polyclonal Antibody

This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. [provided by RefSeq, Nov 2011], function:Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination., similarity:Belongs to the RNA polymerase II subunit 5-mediating protein family., subunit:Component of the URI complex that contains PFD2, POLR2E/RPB5, TIP48, TIP49 and URI. Interacts with POLR2E/RPB5 and LRPPRC., tissue specificity:Ubiquitous.

URI1; C19orf2; NNX3; PPP1R19; RMP; URI; Unconventional prefoldin RPB5 interactor 1; Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RNA polymerase II subunit 5-mediating protein; RPB5-mediating protein