PIG-X Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER) . The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009], function:Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM., pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis., PTM:N-glycosylated., sequence caution:Unusual initiator. The initiator methionine is coded by a non-canonical CTG leucine codon., similarity:Belongs to the PIGX family., subunit:Interacts with PIGM.
Product Name Alternative
PIGX; Phosphatidylinositol-glycan biosynthesis class X protein; PIG-X
Gene Name
PIGX
Gene ID
54965
Swiss Prot
Q8TBF5
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Glycosylphosphatidylinositol (GPI) -anchor biosynthesis
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
26kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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