Involucrin Rabbit Polyclonal Antibody
Product Specifications
Background
Involucrin (IVL) Homo sapiens Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008], function:Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia., PTM:Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide., similarity:Belongs to the involucrin family., subcellular location:Constituent of the scaffolding of the cornified envelope., subunit:Directly or indirectly cross-linked to cornifelin (CNFN) ., tissue specificity:Keratinocytes of epidermis and other stratified squamous epithelia.
Product Name Alternative
IVL; Involucrin
Gene Name
IVL
Gene ID
3713
Swiss Prot
P07476
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
68kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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