HEI10 Rabbit Polyclonal Antibody
Product Specifications
Background
HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G (2) /M.[supplied by OMIM, Apr 2004], function:E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated by CDC2 on serine or threonine residues (in vitro) ., PTM:Ubiquitinated; autoubiquitinated., similarity:Contains 1 RING-type zinc finger., subcellular location:May associate with segregating chromosomes during metaphase and anaphase., subunit:Binds CCNB1 and UBE2L3., tissue specificity:Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.
Product Name Alternative
CCNB1IP1; C14orf18; HEI10; E3 ubiquitin-protein ligase CCNB1IP1; Cyclin-B1-interacting protein 1; Human enhancer of invasion 10
Gene Name
CCNB1IP1
Gene ID
57820
Swiss Prot
Q9NPC3
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
32kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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