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HEI10 Rabbit Polyclonal Antibody

Product Specifications

Background

HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G (2) /M.[supplied by OMIM, Apr 2004], function:E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated by CDC2 on serine or threonine residues (in vitro) ., PTM:Ubiquitinated; autoubiquitinated., similarity:Contains 1 RING-type zinc finger., subcellular location:May associate with segregating chromosomes during metaphase and anaphase., subunit:Binds CCNB1 and UBE2L3., tissue specificity:Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.

Product Name Alternative

CCNB1IP1; C14orf18; HEI10; E3 ubiquitin-protein ligase CCNB1IP1; Cyclin-B1-interacting protein 1; Human enhancer of invasion 10

Gene Name

CCNB1IP1

Gene ID

57820

Swiss Prot

Q9NPC3

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

32kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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