DC-LAMP Rabbit Polyclonal Antibody
Product Specifications
Background
Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]) .[supplied by OMIM, Dec 2010], function:Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells., similarity:Belongs to the LAMP family., tissue specificity:Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues.
Product Name Alternative
Lysosome-associated membrane glycoprotein 3 (LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD antigen CD208)
Gene Name
LAMP3 DCLAMP TSC403
Gene ID
27074
Swiss Prot
Q9UQV4
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Lysosome
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
44kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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