CD64 Rabbit Polyclonal Antibody

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008], function:High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses., online information:FCGR1A mutation db, PTM:N-glycosylated., PTM:Phosphorylated on serine residues., similarity:Belongs to the immunoglobulin superfamily. FCGR1 family., similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., subcellular location:Stabilized at the cell membrane through interaction with FCER1G., subunit:Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL., tissue specificity:Monocyte/macrophage specific.