C7 Rabbit Polyclonal Antibody

C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC) . People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008], disease:Defects in C7 are a cause of component C7 deficiency (C7D) [MIM:217070]. Patients with C7D suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis., function:C7 is a constituent of the membrane attack complex. C7 binds to C5b forming the C5b-7 complex, where it serves as a membrane anchor., online information:C7 mutation db, PTM:C7 has 28 disulfide bridges., similarity:Belongs to the complement C6/C7/C8/C9 family., similarity:Contains 1 EGF-like domain., similarity:Contains 1 LDL-receptor class A domain., similarity:Contains 1 MACPF domain., similarity:Contains 2 Sushi (CCP/SCR) domains., similarity:Contains 2 TSP type-1 domains., subunit:Monomer or dimer; as a C5b-7 complex it can also form multimeric rosettes.